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KMID : 0853020180210010006
Journal of Korean Burn Society
2018 Volume.21 No. 1 p.6 ~ p.11
The Clinical Usefulness of Thermo-Sensitive Hydrogel-Type Allogeneic Keratinocytes for Treatment of Deep Second-Degree Burn
Moon Duk-Ju

Yang Ban-Seok
Shin Jae-Jun
Lee Jong-Ho
Park Su-Jeong
Lee Jung-Sun
Lee Su-Yeon
Abstract
Purpose: Aim of this study was to assess the safety and effectiveness of Keraheal-Allo¢ç (Biosolution Co., Ltd., Korea) in patients with deep second-degree burn as a part of post marketing surveillance.

Methods: Seventy-five patients with deep second-degree burn were enrolled from April 2017 to October 2017. Keraheal-Allo, athermos-sensitive hydrogel-type allogeneic keratinocytes, was applied to 90 deep second-degree burn sites of 75 patients. After application of Keraheal-Allo, the efficacy was assessed as the period of 100% re-epithelialization that was evaluated every time dressing was changed.

Results: The mean re-epithelialization period in the treated sites with KeraHeal-allo was 13.67¡¾5.11 days. There was no severe adverse event.

Conclusion: In conclusion, this thermo-sensitive hydrogel-type allogeneic keratinocytes have the clinical usefulness in terms of the safety, efficacy and ease of use.
KEYWORD
Allogeneic keratinocyte, Thermo-sensitive hydrogel, Deep second degree burn
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